![]() The majority of NB patients present with high-risk disease for which current therapies are ineffective. Neuroblastoma (NB) is a neural crest-derived malignancy mainly occurring in children. Pannexin 1 (PANX1) is expressed in many tissue types including tissues of neural origin. Select the file that you have just downloaded and select import option Reference Manager (RIS). Inhibition of PANX1 Channels Reduces the Malignant Properties of Human High-Risk Neuroblastoma. ![]() Langlois S, St-Pierre ME, Holland SH, Xiang X, Freeman E, Mohamed H, Dural AC, Hammad A, Karami S, van de Panne C, Cowan KN. Cowan, Children's Hospital of Eastern Ontario, Pediatric General Surgery, 401 Smyth Rd, Room 3370, Ottawa, Ontario, K1H 8L1, Canada E-mail: kcowanon.ca Phone: +1 61 (ext. *These authors contributed equally to this work. Department of Surgery, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canadaģ. Molecular Biomedicine Program, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaĢ. ![]() Holland 1,2, Xiao Xiang 1,2, Emily Freeman 1,2, Hisham Mohamed 3, Ahmet Cem Dural 1,3, Ahmed Hammad 1,3, Sanaz Karami 1, Chloé van de Panne 1, Kyle N. ![]() Stéphanie Langlois 1,3*, Marie-Eve St-Pierre 1*, Stephen H. Research Paper Inhibition of PANX1 Channels Reduces the Malignant Properties of Human High-Risk Neuroblastoma ![]()
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